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apalutamide will reduce the extent or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a strong CYP2C19 inducer, with drugs that happen to be CYP2C19 substrates may lead to reduced publicity to these remedies.A calming bedtime plan. Convert off screens at least